Doctors Best - Benfotiamine 150 + Alpha Lipoic Acid 300 VegeCaps 60

Benfotiamine (S-benzoylthiamine-O-monophosphate) is a fat-soluble, synthetic derivative of thiamin (vitamin B1) that is more bioavailable and physiologically active than regular thiamin. It helps maintain healthy cells in the presence of blood glucose, supports protection against oxidative stress, and promotes healthy aging. Alpha-Lipoic Acid, a sulfur-containing fatty acid, aids in defending the body against free radicals and helps recycle antioxidants like vitamin C and vitamin E. As it is soluble in both water and fat, alpha-lipoic acid is often called the "universal antioxidant."

 

Benfotiamine 150mg

Alpha-Lipoic Acid 300mg

L-Leucine 10.5mg

 

Adults: 1 capsule daily with or without food, or as recommended by a nutritionally informed physician

 

Benfotiamine raises the blood level of thiamin pyrophosphate, the biologically active coenzyme of thiamin, and stimulates transketolase, a cellular enzyme essential for maintenance of normal glucose metabolic pathways. Benfotiamine was shown to cause, on average, a 5-fold greater increase in blood thiamin levels than thiamin mononitrate, with a concomitant greater thiamin concentration in red blood cells. Benfotiamine readily passes through intestinal cells and is converted into thiamin. Alpha-lipoic acid is a key factor in the cellular process that metabolizes glucose for energy production. Aging is accompanied by a decreased ability of the liver to recycle ascorbic acid following oxidative stress. R-lipoic acid, after two weeks of supplementation to aged rats, reversed the age-related impairment of ascorbic acid recycling and concentration in liver cells. Aging is associated with oxidative stress in the brain. The brains high rate of metabolism and its long-lived neurons make it particularly vulnerable to oxidative stress. Since alpha-lipoic acid interrupts cellular oxidative processes in both its oxidized and reduced forms, it plays a modulatory in the brain and nervous system.

 

Support for healthy ageing – Benfotiamine has several means of fighting the ageing process. By stimulating transketolase this can reduce the production on Advanced Glycation End Products (AGEs)

 

A Logical Merge – Benfotiamine and Alpha Lipoic Acid are two bioactive compounds that share common goals, in particular areas of health, albeit via different mechanisms. Best Benfotiamine 150 + ALA 300 is a sensible combination to oppose the oxidative stress that accelerates ageing, to promote maintenance of healthy glucose metabolism and to support a healthy nervous system.